Dr. Howe and Dr. Fish
Dr. Fish
Dr. Howe and Dr. Fish
- Raju S, Botts S, Blaser M, Abdul-Samad M, Prajapati K, Khosraviani N, Ho TWW, Breda LCD, Ching C, Galant NJ, Fiddes L, Wu R, Clift CL, Pham T, Lee WL, Singh SA, Aikawa E, Fish J, Howe KL. Directional endothelial communication by polarized extracellular vesicle release. Circulation Reserarch. 2024 Jan 4. https://doi.org/10.1161/CIRCRESAHA.123.322993
- Hanneman K, Houbois C, Kei T, Gustafson D, Thampinathan B, Sooriyakanthan M, Fish JE, Howe KL, Cheung AM, Wintersperger BJ, Gold WL, Woo A, Thavendiranathan P. Multimodality Cardiac Imaging, Cardiac Symptoms, and Clinical Outcomes in Patients Who Recovered from Mild COVID-19. Radiology. 2023 Jul;308(1):e230767. doi: 10.1148/radiol.230767. PMID: 37432085.
- Patel S, Guo MK, Abdul Samad M, Howe KL. Extracellular vesicles as biomarkers and modulators of atherosclerosis pathogenesis. Front Cardiovasc Med. 2023 May 26;10:1202187. doi: 10.3389/fcvm.2023.1202187. PMID: 37304965; PMCID: PMC10250645.
- Guo X, Khosraviani N, Raju S, Singh J, Farahani NZ, Abramian M, Torres VJ, Howe KL, Fish JE, Kapus A, Lee WL. Endothelial ACKR1 is induced by neutrophil contact and down-regulated by secretion in extracellular vesicles. Front Immunol. 2023 Apr 21;14:1181016. doi: 10.3389/fimmu.2023.1181016. PMID: 37153544; PMCID: PMC10160463.
- Marschner CA, Thavendiranathan P, Gustafson D, Howe KL, Fish JE, Iwanochko RM, Wald RM, Abdel-Qadir H, Epelman S, Cheung AM, Hong R, Hanneman K. Myocardial Inflammation on FDG PET/MRI and Clinical Outcomes in Symptomatic and Asymptomatic Participants after COVID-19 Vaccination. Radiol Cardiothorac Imaging. 2023 Mar 9;5(2):e220247. doi: 10.1148/ryct.220247. PMID: 36987440; PMCID: PMC10037313.
- Howe KL, Cybulsky M, Fish JE. The Endothelium as a Hub for Cellular Communication in Atherogenesis: Is There Directionality to the Message? Front Cardiovasc Med. 2022 Apr 15;9:888390. doi: 10.3389/fcvm.2022.888390. PMID: 35498030; PMCID: PMC9051343.
- Gustafson D, Ngai M, Wu R, Hou H, Schoffel AC, Erice C, Mandla S, Billia F, Wilson MD, Radisic M, Fan E, Trahtemberg U, Baker A, McIntosh C, Fan CS, Dos Santos CC, Kain KC, Hanneman K, Thavendiranathan P, Fish JE, Howe KL. Cardiovascular signatures of COVID-19 predict mortality and identify barrier-stabilizing therapies. EBioMedicine. 2022 Apr;78:103982. doi: 10.1016/j.ebiom.2022.103982. Epub 2022 Apr 8. PMID: 35405523; PMCID: PMC8989492.
- Lu, RXZ, Lai BFL, Rafatian N, Gustafson D, Campbell SB, Banerjee A, Kozak R, Mossman K, Mubareka S, Howe KL, Fish JE, Radisic M. 2022. Vasculature-on-a-chip platform with innate immunity enables identification of angiopoietin-1 derived peptide as a therapeutic for SARS-CoV-2 induced inflammation. Lab on a chip, 22(6), 1171–1186. https://doi.org/10.1039/d1lc00817j
- Hanneman K, Houbois C, Schoffel A, Gustafson D, Iwanochko RM, Wintersperger BJ, Chan R, Fish JE, Howe KL, Thavendiranathan P. Combined Cardiac Fluorodeoxyglucose-Positron Emission Tomography/Magnetic Resonance Imaging Assessment of Myocardial Injury in Patients Who Recently Recovered From COVID-19. JAMA Cardiol. 2022 Mar 1;7(3):298-308. doi: 10.1001/jamacardio.2021.5505. PMID: 35019953; PMCID: PMC8756363.
- Veitch S, Njock MS, Chandy M, Siraj MA, Chi L, Mak H, Yu K, Rathnakumar K, Perez-Romero CA, Chen Z, Alibhai FJ, Gustafson D, Raju S, Wu R, Zarrin Khat D, Wang Y, Caballero A, Meagher P, Lau E, Pepic L, Howe KL, … Fish JE. MiR-30 promotes fatty acid beta-oxidation and endothelial cell dysfunction and is a circulating biomarker of coronary microvascular dysfunction in pre-clinical models of diabetes. Cardiovascular diabetology. 2022 Feb; 21(1), 31. https://doi.org/10.1186/s12933-022-01458-z
- Botts SR, Fish JE, Howe KL. Dysfunctional Vascular Endothelium as a Driver of Atherosclerosis: Emerging Insights Into Pathogenesis and Treatment. Front Pharmacol. 2021 Dec 22;12:787541. doi: 10.3389/fphar.2021.787541. PMID: 35002720; PMCID: PMC8727904.
Dr. Fish
- Krohn JB, Aikawa E, Aikawa M, Hutcheson JD, Sahoo S, Fish JE. Editorial: Extracellular vesicles in cardiovascular inflammation and calcification. Front Cardiovasc Med. 2022 Nov 8;9:1077124. doi: 10.3389/fcvm.2022.1077124. PMID: 36426218; PMCID: PMC9680153.
- Wälchli T, Farnhammer F, Fish JE. MicroRNA-Based Regulation of Embryonic Endothelial Cell Heterogeneity at Single-Cell Resolution. Arterioscler Thromb Vasc Biol. 2022 Mar;42(3):343-347. doi: 10.1161/ATVBAHA.122.317400. Epub 2022 Feb 23. PMID: 35196110.
- Khosraviani N, Wu R, Fish JE. Angiopoietin-2: An Emerging Tie to Pathological Vessel Enlargement. Arterioscler Thromb Vasc Biol. 2022 Jan;42(1):3-5. doi: 10.1161/ATVBAHA.121.317102. Epub 2021 Nov 11. PMID: 34758631.
- Aghel N, Gustafson D, Di Meo A, Music M, Prassas I, Seidman MA, Hansen AR, Thavendiranathan P, Diamandis EP, Delgado D, Fish JE. Recurrent Myocarditis Induced by Immune-Checkpoint Inhibitor Treatment Is Accompanied by Persistent Inflammatory Markers Despite Immunosuppressive Treatment. JCO Precis Oncol. 2021 Mar 11;5:PO.20.00370. doi: 10.1200/PO.20.00370. PMID: 34337287; PMCID: PMC8238280.
- Ching C, Gustafson D, Thavendiranathan P, Fish JE. Cancer therapy-related cardiac dysfunction: is endothelial dysfunction at the heart of the matter? Clin Sci (Lond). 2021 Jun 25;135(12):1487-1503. doi: 10.1042/CS20210059. PMID: 34136902.
- Fish JE, Flores Suarez CP, Boudreau E, Herman AM, Gutierrez MC, Gustafson D, DiStefano PV, Cui M, Chen Z, De Ruiz KB, Schexnayder TS, Ward CS, Radovanovic I, Wythe JD. Somatic Gain of KRAS Function in the Endothelium Is Sufficient to Cause Vascular Malformations That Require MEK but Not PI3K Signaling. Circ Res. 2020 Aug 28;127(6):727-743. doi: 10.1161/CIRCRESAHA.119.316500. Epub 2020 Jun 17. PMID: 32552404; PMCID: PMC7447191.
- Khyzha N, Khor M, DiStefano PV, Wang L, Matic L, Hedin U, Wilson MD, Maegdefessel L, Fish JE. Regulation of CCL2 expression in human vascular endothelial cells by a neighboring divergently transcribed long noncoding RNA. Proc Natl Acad Sci U S A. 2019 Aug 13;116(33):16410-16419. doi: 10.1073/pnas.1904108116. Epub 2019 Jul 26. PMID: 31350345; PMCID: PMC6697820.
- Nikolaev SI, Vetiska S, Bonilla X, Boudreau E, Jauhiainen S, Rezai Jahromi B, Khyzha N, DiStefano PV, Suutarinen S, Kiehl TR, Mendes Pereira V, Herman AM, Krings T, Andrade-Barazarte H, Tung T, Valiante T, Zadeh G, Tymianski M, Rauramaa T, Ylä-Herttuala S, Wythe JD, Antonarakis SE, Frösen J, Fish JE, Radovanovic I. Somatic Activating KRAS Mutations in Arteriovenous Malformations of the Brain. N Engl J Med. 2018 Jan 18;378(3):250-261. doi: 10.1056/NEJMoa1709449. Epub 2018 Jan 3. PMID: 29298116; PMCID: PMC8161530.